BAY 2416964

BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment.


Cat. No.: EX-A4271	Purity: >98%

	Chemical structure of BAY 2416964

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	400	In-stock
250mg	700	In-stock
500mg	1000	In-stock
1g	1550	In-stock
2g	2500	In-stock
5g	4850	In-stock

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Synonyms	BAY2416964
CAS No.	2242464-44-2
Purity	>98%
Formula	C18H18ClN5O3
Mol Weight	387.82
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kober, Christina et al. “Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy.” Journal for immunotherapy of cancer vol. 11,11 (2023): e007495. doi:10.1136/jitc-2023-007495 [2]. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1
CoA	CoA of BAY 2416964

Smiles:	O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CN(C)N=C3)C1=O)N[C@@H](C)CO


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